Capabilities
Non-Sterile Compounding: USP <795> Explained
Non-sterile compounding is the preparation of medications that don't need to be sterile — such as capsules, creams and ointments, oral suspensions, and troches — in a clean, controlled (but non-cleanroom) environment. It is governed by USP General Chapter <795>, which sets standards for ingredients, equipment, documentation, and beyond-use dating.
Key takeaways
- Non-sterile compounding covers oral, topical, and other non-injected forms.
- Governed by USP <795>.
- Common forms: capsules, creams/ointments, oral suspensions, troches, suppositories.
- Logos RX operates a dedicated non-sterile compounding lab.
What non-sterile compounding covers
Most customized oral and topical medications are non-sterile preparations. Because they aren't injected or applied to the eye, they don't require a cleanroom — but they still demand careful technique, quality ingredients, and documentation under USP <795>.
- Capsules in custom strengths or dye/filler-free bases.
- Topical creams, gels, and ointments.
- Oral suspensions and solutions (often flavored).
- Troches and lozenges.
- Suppositories.
How quality is maintained
USP <795> addresses ingredient sourcing and identity, equipment cleaning, master formulation and compounding records, and beyond-use dating so that each non-sterile preparation is consistent and safe. Logos RX prepares non-sterile medications to each prescription in a dedicated <795> lab.
Frequently asked questions
Can non-sterile compounded medications be flavored?
Yes. Flavoring oral suspensions and liquids is a common non-sterile compounding service, especially for pediatric and veterinary patients who won't take an unflavored medication.
Related reading
Work with a 503A compounding pharmacy
Logos RX compounds personalized medications in Tampa and ships nationwide within our licensed states. Providers can prescribe through our portal.
Educational content. Compounded medications are not FDA-approved and require a prescription. Last reviewed June 2026.