Injectable
CyanocobalaminCommercially available Vitamin B12
A stable, commercially available form of injectable vitamin B12 used to restore and maintain healthy B12 status.
- Converted to the active coenzymes methylcobalamin and 5-deoxyadenosylcobalamin
- Supports red blood cell formation, DNA synthesis, and CNS function
- Restores B12 status in deficiency, malabsorption, or dietary insufficiency
- 1,000 mcg/mL multi-dose vial
About the ingredient
Cyanocobalamin (Vitamin B12)
A stable, synthetic form of vitamin B12 converted in the body into the active cobalamin coenzymes methylcobalamin and 5-deoxyadenosylcobalamin — a key cofactor for methionine synthase and L-methylmalonyl-CoA mutase.
Cyanocobalamin is a stable, synthetic form of vitamin B12 that is converted in the body into the active cobalamin coenzymes methylcobalamin and 5-deoxyadenosylcobalamin. Vitamin B12 is essential for healthy red blood cell formation, DNA synthesis, central nervous system function, myelin support, and normal cellular metabolism. Clinically, cyanocobalamin is commonly used to restore and maintain adequate B12 status in patients with deficiency, malabsorption, increased requirements, or dietary insufficiency.
Mechanistically, vitamin B12 serves as a key cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Through these pathways, it supports methylation, homocysteine metabolism, fatty acid metabolism, neurologic integrity, and hematopoiesis. Deficiency can present with fatigue, weakness, glossitis, megaloblastic anemia, numbness or tingling, balance changes, cognitive symptoms, and neurologic findings that may occur even before anemia is obvious.
From a clinical standpoint, cyanocobalamin is especially relevant in patients with pernicious anemia, gastric or intestinal surgery, gastrointestinal malabsorption, long-term metformin or acid-suppressing medication use, vegetarian or vegan dietary patterns, and other conditions that impair B12 intake or absorption. Because absorption of food-bound B12 depends on gastric acid, intrinsic factor, and distal ileal function, injectable or other clinician-directed forms may be preferred when absorption is unreliable.
Essential methylation cofactor
Serves as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase, supporting methylation, homocysteine metabolism, and fatty acid metabolism.
Hematopoiesis and nerve health
Essential for healthy red blood cell formation, DNA synthesis, myelin support, and neurologic integrity.
Reliable when absorption is impaired
Injectable B12 bypasses dependence on gastric acid, intrinsic factor, and ileal function — preferred when food-bound B12 absorption is unreliable.
How to take
A consistent routine matters.
Follow the specific directions from your healthcare provider. These steps are a general reference for injectable administration.
- 1
Inspect the vial — solution should be clear and free of particles before each use.
- 2
Clean the vial stopper with a fresh alcohol swab and let it air-dry.
- 3
Draw the prescribed dose using an insulin syringe; tap out any air bubbles.
- 4
Inject subcutaneously into the abdomen, thigh, or upper arm, rotating sites each dose.
- 5
Discard the used syringe immediately in an FDA-cleared sharps container.
Product Details
Available formulations
| Vial Total mg | Concentration | mL |
|---|---|---|
| 10,000 mcg | 1,000 mcg/mL | 10 mL |
Typical dosage & titration
Recommended titration schedule
Reference schedule only — your provider may adjust the timing or dose based on your individual response and lab work.
| Weeks | Units | MG | ML | SIG / Directions |
|---|---|---|---|---|
| 1–4 | 50 | 500 mcg | 0.50 mL | Inject 50 units subcutaneously or intramuscularly once daily, Monday through Friday. |
FAQ
Frequently asked questions
Provider workflow
Ready to prescribe Cyanocobalamin?
Submit a prescription through the Logos RX provider portal, or reach out to our pharmacy team for formulary, dosing, or patient-onboarding questions.
Cyanocobalamin
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